What Are Polynucleotides?
Polynucleotides are an advanced skin booster treatment used to support skin regeneration and improve visible signs of ageing. Made up of long chains of DNA, they work at a cellular level to stimulate repair and encourage collagen production, helping to improve skin texture, firmness, elasticity and overall skin quality over time.
​
At our clinics in Hampshire, we use polynucleotides derived from purified fragments of salmon DNA, chosen for their close compatibility with human DNA and their regenerative properties.
​
Treatment is delivered through a series of gentle microinjections, typically carried out over two to three sessions, allowing the skin to gradually repair and strengthen.
Following treatment, small raised areas may be visible on the skin, which usually settle within 72 hours as the product is absorbed.


What Can Polynucleotides
Be Used For?
Polynucleotides are a versatile skin regeneration treatment that can be used to improve overall skin quality and address a range of concerns.
Rather than adding volume, Polynucleotides work by supporting the skin’s natural repair processes, making them ideal for areas where the skin is thinner or more delicate. They can be used to -
Improve skin texture and tone - Helping to smooth uneven texture and improve overall skin quality.
Increase firmness and elasticity - By stimulating collagen production, the skin becomes stronger, firmer and more resilient over time.
​
Reduce the appearance of fine lines - Supporting skin regeneration can soften fine lines, particularly in fragile areas.
Treat delicate areas - Including the under-eye area, face, neck and décolletage, where traditional fillers may not be suitable.​​
Why Should You Choose Our Hampshire Clinic For Polynculeotides?
At Secret Skin in Hampshire, we place your comfort, safety and results at the centre of everything we do. With a strong medical background and a meticulous approach to aesthetics, we carry out every treatment with precision, care and attention to detail, always guided by what will work best for you.
​
We recognise that no two faces are the same, which is why our approach is highly personalised. Each treatment is thoughtfully planned to enhance your natural features rather than change them, creating results that are subtle, balanced and in keeping with your overall appearance.
Our focus is on refinement, not transformation - delivering aesthetic treatments that help you look refreshed, confident and like the best version of yourself.
Frequently Asked Questions
How Long Do Polynucleotides Take To Work?
You’ll notice results following your polynucleotide appointment almost immediately. However, the full effects will take a few weeks to appear. This is because Polynucleotides work at a cellular rather than a surface level.
Small bumps on the skin will typically subside within 72 hours, revealing the complete outcome of your treatment.
How Long Will The Effects Of My Polynucleotide
Treatment Last?
The longevity of your treatment will depend on where it’s administered. However, in general the results of polynucleotides can last for up to six months. Nurse Louise will advise you how often you’ll require follow-up appointments to maintain your desired results.
Who Are Polynucleotides Suitable For?
Polynucleotides are mostly used to treat the visible signs of ageing including fine lines and wrinkles. However, they can also effectively address acne scarring, hydration, under eye discolouration and even hair loss.
How Should I Prepare For My Polynucleotide Treatment?
Before your treatment, you must avoid blood-thinning medications and alcohol. It’s also important that you arrive make-up free. Nurse Louise will provide you with personalised pre-treatment instructions during your consultation.
Where Can I Get Polynucleotides?
Polynucleotide injections are highly versatile. They can be administered in the cheeks, forehead, around the eyes and lips. For hair loss, they can be injected into the scalp.
Are Polynucleotides Safe?
Polynucleotides are completely safe, and our practitioners are each medically and complications trained. We understand that you may still have some concerns, which is why we’ll invite you to an in-depth consultation prior to your treatment to address any questions you have.
